徐立朋

博士/副教授/硕士研究生导师

通讯地址:              暨南大学药学院,广州市黄埔大道西601号,邮编:510632
E-mail:                    xulipeng2000@163.com

教育经历:                                                                                        

2003 - 2006              博士(药理学),中山大学
2006 - 2008              博士后,美国伊利诺伊大学
 
工作经历:     
2008 - 至今              暨南大学药学院新药研究所,副教授,硕士研究生导师
 
研究方向:         
内分泌和抗炎免疫药理学

研究成果:              
主持国家自然科学基金2项及广东省科技计划重点项目、教育部留学回国启动基金、教育部博士学科点专项科研基金、暨南大学引进优秀人才科研启动基金各1项,作为主要成员参与了国家“十一五”科技重大专项课题2项、广东省科技攻关计划项目-中医药重大专项1项;目前已发表研究论文40余篇,申请并获授权发明专利5项。
 
荣誉与奖励:
教学成果荣获2018年广东省计算机教育软件评审三等奖及第二十二届全国教师教育教学信息化交流活动大赛二等奖。
 

发表的部分论文 (English)

 

1. Yali Yang1, Hui Yan1, Mei Jing, Zaijun Zhang, Gaoxiao Zhang, Yewei Sun, Luchen Shan, Pei Yu, Yuqiang Wang, Lipeng Xu*. Andrographolide derivative AL-1 ameliorates TNBS-induced colitis in mice: involvement of NF-кB and PPAR-γ signaling pathways. Sci Rep. 2016 Jul 20; 6: 29716. 

2. Hui Yan1, Yongmei Li1, Yali Yang, Zaijun Zhang, Gaoxiao Zhang, Yewei Sun, Pei Yu, Yuqiang Wang, Lipeng Xu*. Protective effects of andrographolide Derivative AL-1 on high glucose-induced oxidative stress in RIN-m cells. Curr Pharm Des. 2016;22(4):499-505. (1共同第一作者) 

3. Jinxian Huang1, Lipeng Xu1, Qiuju Huang, Jiani Luo, Peiqing Liu, Shaorui Chen, Xi Yuan, Yao Lu, Ping Wang, Sigui Zhou. Changes in short-chain acyl-coA dehydrogenase during rat cardiac development and stress. J Cell Mol Med. 2015 Jul; 19(7):1672-88. 

4. Yongmei Li, Hui Yan, Zaijun Zhang, Gaoxiao Zhang, Yewei Sun, Pei Yu, Yuqiang Wang, Lipeng Xu*. Andrographolide derivative AL-1 improves insulin resistance through down-regulation of NF-κB signaling pathway. Br J Pharmacol. 2015 Jun; 172(12): 3151-8. 

5. Lipeng Xu, Yongmei Li, Sainan Wan, Yuqiang Wang, Pei Yu. Protective effects of apocynin nitrone on acute lung injury induced by lipopolysaccharide in rats. Int Immunopharmacol. 2014, 20(2): 377-82. 

6. Ping Wang1, Sigui Zhou1, Lipeng Xu1, Yao Lu, Xi Yuan, Huijie Zhang, Ruifang Li, Jian Fang, Peiqing Liu. Hydrogen peroxide-mediated oxidative stress and collagen synthesis in cardiac fibroblasts: Blockade by tanshinone IIA. J Ethnopharmacol. 2013, 145(1): 152-61. 

7. Sigui Zhou, Xi Yuan, Qinghua Liu, Xiaoqi Zhang, Xuediao Pan, Linquan Zang, Lipeng Xu*. BAPTA-AM, an intracellular calcium chelator, inhibits RANKL-induced bone marrow macrophages differentiation through MEK/ERK, p38 MAPK and Akt, but not JNK pathways. Cytokine. 2010, 52(3):210-4.

8. Hongli Sun, Lipeng Xu*, Pei Yu, Jie Jiang, Gaoxiao Zhang, Yuqiang Wang *.Synthesis and preliminary evaluation of neuroprotection of celastrol analogues in PC12 cells. Bioorg. Med. Chem. Lett. 2010, 20(13): 3844-7.

9. Youmin Kang1, Lipeng Xu1, Bin Wang, Aoshuang Chen, and Guoxing Zheng. Immunosuppressant as adjuvant for tolerogenic immunization. J Immunol. 2008, 180(8): 5172-6. (1共同第一作者)

 

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